Miha studied biotechnology in Ljubljana, Munich and Cambridge. In 2017 Miha finished his PhD at the LMU Munich/Helmholtz Zentrum Munich working at the crosstalk between RNA biochemistry and developmental biology. Miha in 2018 pursued his postdoc at The Francis Crick Institute under the mentorship of Jernej Ule. Upon receiving the postdoc-to-PI Wellcome Trust ECR fellowship in 2020, Miha Modic was initially a Sir Henry Wellcome Senior Fellow in the Ule lab and in 2023 started his independent research group as King’s Prize Fellow spanning between King’s College London and the National Institute of Chemistry. In 2025 Miha accepted a call to the Carl Zeiss Center of Synthetic Genomics between Uni Heidelberg, Mainz & KIT, where he is currently professor and Head of Department for Genomics and Development at the Karlsruhe Institute of Technology.

We investigate how RNA-binding proteins and RNAs assemble into biomolecular condensates that coordinate gene expression with high spatial and temporal precision during cell fate decisions. To achieve this, we develop and apply experimental and computational approaches to map RNA–RNA and RNA–protein interaction networks, identify the molecular principles governing condensate formation, and engineer synthetic RNA systems to probe their biological function. In parallel, we develop machine learning and bioinformatic methods to predict RNA–protein interactions and decode post-transcriptional regulatory networks. By integrating molecular biology, genomics, synthetic biology, and artificial intelligence, we aim to reveal fundamental principles of gene regulation and apply them to understand development and human disease.